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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PEX1
All Species:
5.76
Human Site:
S444
Identified Species:
7.92
UniProt:
O43933
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43933
NP_000457.1
1283
142867
S444
V
T
P
K
I
P
R
S
L
K
L
Q
P
R
E
Chimpanzee
Pan troglodytes
XP_519198
1283
142803
S444
V
T
P
K
I
P
R
S
L
K
L
Q
P
R
E
Rhesus Macaque
Macaca mulatta
XP_001101055
1278
142022
P442
V
E
V
T
P
K
I
P
R
S
L
K
L
Q
P
Dog
Lupus familis
XP_532459
1267
140567
R428
E
I
T
P
K
I
P
R
S
L
K
L
Q
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q5BL07
1284
141409
K445
P
K
I
P
R
S
L
K
L
Q
P
R
E
N
L
Rat
Rattus norvegicus
P46462
806
89330
L51
P
K
M
D
E
L
Q
L
F
R
G
D
T
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520628
1178
126535
P409
T
E
R
S
P
K
T
P
T
A
L
Q
L
Q
P
Chicken
Gallus gallus
XP_418655
1290
143066
N452
L
R
L
Q
P
K
Q
N
L
H
K
D
T
R
E
Frog
Xenopus laevis
P23787
805
89193
Q50
Q
A
K
M
D
E
L
Q
L
F
R
G
D
T
V
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
L51
A
K
M
D
E
L
Q
L
F
R
G
D
T
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
L46
S
Q
A
K
M
D
E
L
Q
L
F
R
G
D
T
Honey Bee
Apis mellifera
XP_397107
1069
120490
T314
E
L
V
V
R
V
Y
T
L
E
D
L
L
E
K
Nematode Worm
Caenorhab. elegans
P54812
810
89622
L55
S
Q
A
K
M
D
E
L
G
L
F
R
G
D
S
Sea Urchin
Strong. purpuratus
XP_797089
1508
166130
M598
L
F
D
L
K
D
N
M
N
E
T
M
I
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SCN8
815
90322
D60
K
L
Q
L
F
R
G
D
T
I
L
I
K
G
K
Baker's Yeast
Sacchar. cerevisiae
P24004
1043
117258
N288
C
D
S
Q
I
P
E
N
H
I
A
L
S
S
H
Red Bread Mold
Neurospora crassa
Q7SGP2
1381
148356
K494
F
F
E
A
Q
S
Q
K
S
N
P
P
A
Y
T
Conservation
Percent
Protein Identity:
100
99.6
92.8
86.4
N.A.
82
23.3
N.A.
52.4
62.4
22.9
22.8
N.A.
23.6
27.6
22.1
35.2
Protein Similarity:
100
100
94.9
92
N.A.
89.5
39.2
N.A.
66
77.6
38.6
39
N.A.
37.6
46.7
38.4
53.2
P-Site Identity:
100
100
13.3
0
N.A.
6.6
0
N.A.
13.3
20
6.6
0
N.A.
6.6
6.6
6.6
0
P-Site Similarity:
100
100
26.6
0
N.A.
20
13.3
N.A.
20
46.6
6.6
13.3
N.A.
20
26.6
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.5
25.7
21.4
Protein Similarity:
N.A.
N.A.
N.A.
38.5
45.2
40.9
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
6
12
6
0
0
0
0
0
6
6
0
6
0
0
% A
% Cys:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
6
6
12
6
18
0
6
0
0
6
18
6
12
0
% D
% Glu:
12
12
6
0
12
6
18
0
0
12
0
0
6
6
18
% E
% Phe:
6
12
0
0
6
0
0
0
12
6
12
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
6
0
6
0
12
6
12
6
0
% G
% His:
0
0
0
0
0
0
0
0
6
6
0
0
0
0
6
% H
% Ile:
0
6
6
0
18
6
6
0
0
12
0
6
6
0
0
% I
% Lys:
6
18
6
24
12
18
0
12
0
12
12
6
6
0
12
% K
% Leu:
12
12
6
12
0
12
12
24
36
18
30
18
18
6
18
% L
% Met:
0
0
12
6
12
0
0
6
0
0
0
6
0
0
0
% M
% Asn:
0
0
0
0
0
0
6
12
6
6
0
0
0
6
0
% N
% Pro:
12
0
12
12
18
18
6
12
0
0
12
6
12
6
12
% P
% Gln:
6
12
6
12
6
0
24
6
6
6
0
18
6
12
0
% Q
% Arg:
0
6
6
0
12
6
12
6
6
12
6
18
0
18
12
% R
% Ser:
12
0
6
6
0
12
0
12
12
6
0
0
6
6
6
% S
% Thr:
6
12
6
6
0
0
6
6
12
0
6
0
18
6
12
% T
% Val:
18
0
12
6
0
6
0
0
0
0
0
0
0
12
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
6
0
0
0
0
0
0
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _